What kind of information would be required if karyotype analysis were to e used to detct the genetic disord?

What kind of information would be required if karyotype analysis were to e used to detct the genetic disorders of real organisms?What kind of information would be required if karyotype analysis were to e used to detct the genetic disord?1. The chromosome number of normal individuals of this species.



2. A karyotype of a normal individual of this species would be of great help for comparison -- it'll enable you to see, through banding patterns and length, changes that don't affect the chromosome number. These would include things like

a piece of one chromosome getting stuck onto another chromosome (either translocated or duplicated)

a piece of chromosome that's "upside down" (inversion)

a piece of chromosome that's missing (deletion)